MRCP:- USMLE Hematology Qbank mcq medical question: Diagnosis and management of von Willebrand' disease

[student01]

USMLE Hematology Qbank mcq medical question: Diagnosis and management of von Willebrand' disease
A 31-year-old man was sent to your clinic by his dentist to be evaluated for gingival bleeding prior to tooth extraction. For the past two months the patient has been experiencing bleeding from his gums while brushing. He admits to several episodes of nosebleeds throughout his lifetime, which were somewhat severe and once required a visit to the emergency department. He denies melena, hematochezia, joint pain, or swelling. His father died at an early age of an unknown cause, and patient recalls that he also had nosebleeds.

His vitals in your office are stable. His physical examination is unremarkable. No petechiae or purpura are seen on the skin. The oral mucosa is normal. The spleen is not palpable, and there are no joint deformities.

Laboratory studies show the following:

WBC 6,200/mm3; hematocrit 38%; platelets 360,000/mm3; PT 11.6 seconds; PTT 48.0 seconds; INR 1.3.

Peripheral smear is normal, and bleeding time is mildly prolonged. The ristocetin cofactor activity is abnormal.

What would you do to make the dental extraction safe?

A) Desmopressin
B) No therapy
C) Aminocaproic acid
D) Factor VIII concentrate infusion
E) Cryoprecipitate






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[sadeek]

Excellent hematology mcq question
thanks

[Lalika367]

Wow... I cudnt answer single Out Of Hematology Q Bank... Arghhh..

[MOHDASHRAF]

CORRECT ANSWER E

[zzzrrr]

thanks a lot very much

[Confident]

Factor VIII concentrate infusion.
Also Desmopressin and Cryoprecipitate are choices for the treatment of Von Willebrand's disease

[sarajafar]

D)factor VIII concentrate infusion

[arvarita]

it should be A

[gautam1825]

Amino caproic acid prophylactic

[Naifhadi]

ThankssDddddddddddddd